SCOP 1.75: Domain d1auia_: 1aui A:

Lineage for d1auia_ (1aui A:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.159: Metallo-dependent phosphatases [56299] (1 superfamily)
   4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication

4. Superfamily d.159.1: Metallo-dependent phosphatases [56300] (12 families)
   different families of this superfamily are groupped in a single Pfam family, Pfam PF00149

5. Family d.159.1.3: Protein serine/threonine phosphatase [56310] (5 proteins)

6. Protein Protein phosphatase-2B (PP-2B, calcineurin A subunit) [56313] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56315] (4 PDB entries)

8. Domain d1auia_: 1aui A: [42085]
   Other proteins in same PDB: d1auib_
   complexed with ca, fe, zn

Details for d1auia_

PDB Entry: 1aui, 2.1 Å

PDB Description: human calcineurin heterodimer

PDB Compounds: (A:) serine/threonine phosphatase 2b

SCOP Domain Sequences for d1auia_:

Sequence, based on SEQRES records:

>d1auia_ d.159.1.3 (A:) Protein phosphatase-2B (PP-2B, calcineurin A subunit) {Human (Homo sapiens) [TaxId: 9606]}
tdrvvkavpfppshrltakevfdndgkprvdilkahlmkegrleesvalriitegasilr
qeknlldidapvtvcgdihgqffdlmklfevggspantrylflgdyvdrgyfsiecvlyl
walkilypktlfllrgnhecrhlteyftfkqeckikyservydacmdafdclplaalmnq
qflcvhgglspeintlddirkldrfkeppaygpmcdilwsdpledfgnektqehfthntv
rgcsyfysypavceflqhnnllsilraheaqdagyrmyrksqttgfpslitifsapnyld
vynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvtemlvnvlnics
ddelgseedgfdgataaarkevirnkiraigkmarvfsvlreesesvltlkgltptgmlp
sgvlsggkqtlqsatveaieadeaikgfspqhkitsfeeakgldrinermppr

Sequence, based on observed residues (ATOM records):

>d1auia_ d.159.1.3 (A:) Protein phosphatase-2B (PP-2B, calcineurin A subunit) {Human (Homo sapiens) [TaxId: 9606]}
tdrvvkavpfppshrltakevfdndgkprvdilkahlmkegrleesvalriitegasilr
qeknlldidapvtvcgdihgqffdlmklfevggspantrylflgdyvdrgyfsiecvlyl
walkilypktlfllrgnhecrhlteyftfkqeckikyservydacmdafdclplaalmnq
qflcvhgglspeintlddirkldrfkeppaygpmcdilwsdpledfgnektqehfthntv
rgcsyfysypavceflqhnnllsilraheaqdagyrmyrksqttgfpslitifsapnyld
vynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvtemlvnvlnics
sfeeakgldrinermppr

Timeline for d1auia_:

• d1auia_ first appeared (with stable ids) in SCOP 1.55
  
• d1auia_ appears in SCOP 1.73
  
• d1auia_ appears in SCOPe 2.01
  
• d1auia_ appears in the current release, SCOPe 2.08