Lineage for d1tcoa_ (1tco A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2231921Fold d.159: Metallo-dependent phosphatases [56299] (1 superfamily)
    4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication
  4. 2231922Superfamily d.159.1: Metallo-dependent phosphatases [56300] (13 families) (S)
    different families of this superfamily are groupped in a single Pfam family, Pfam PF00149
  5. 2232001Family d.159.1.3: Protein serine/threonine phosphatase [56310] (6 proteins)
  6. 2232072Protein Protein phosphatase-2B (PP-2B, calcineurin A subunit) [56313] (2 species)
  7. 2232073Species Cow (Bos taurus) [TaxId:9913] [56314] (1 PDB entry)
  8. 2232074Domain d1tcoa_: 1tco A: [42084]
    Other proteins in same PDB: d1tcob_, d1tcoc_
    complexed with ca, fe, fk5, myr, po4, zn

Details for d1tcoa_

PDB Entry: 1tco (more details), 2.5 Å

PDB Description: ternary complex of a calcineurin a fragment, calcineurin b, fkbp12 and the immunosuppressant drug fk506 (tacrolimus)
PDB Compounds: (A:) serine/threonine phosphatase b2

SCOPe Domain Sequences for d1tcoa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1tcoa_ d.159.1.3 (A:) Protein phosphatase-2B (PP-2B, calcineurin A subunit) {Cow (Bos taurus) [TaxId: 9913]}
vpfppshrltakevfdndgkprvdilkahlmkegrleetvalriitegasilrqeknlld
idapvtvcgdihgqffdlmklfevggspantrylflgdyvdrgyfsiecvlylwalkily
pktlfllrgnhecrhlteyftfkqeckikyservydacmdafdclplaalmnqqflcvhg
glspeintlddirkldrfkeppaygpmcdilwsdpledfgnektqehfthntvrgcsyfy
sypavceflqhnnllsilraheaqdagyrmyrksqttgfpslitifsapnyldvynnkaa
vlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvtemlvnvlnic

SCOPe Domain Coordinates for d1tcoa_:

Click to download the PDB-style file with coordinates for d1tcoa_.
(The format of our PDB-style files is described here.)

Timeline for d1tcoa_: