Lineage for d7a1ka_ (7a1k A:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2814470Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2815433Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2815654Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)
  6. 2815655Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)
  7. 2815656Species Human (Homo sapiens) [TaxId:9606] [82196] (38 PDB entries)
  8. 3083835Domain d7a1ka_: 7a1k A: [420152]
    automated match to d2xuma_
    complexed with qvz, so4, zn

Details for d7a1ka_

PDB Entry: 7a1k (more details), 1.99 Å

PDB Description: factor inhibiting hif-1 alpha in complex with zn(ii) and 3-((9,9- dimethyl-9h-fluoren-2-yl)methyl)-2-oxoglutarate
PDB Compounds: (A:) Hypoxia-inducible factor 1-alpha inhibitor

SCOPe Domain Sequences for d7a1ka_:

Sequence; same for both SEQRES and ATOM records: (download)

>d7a1ka_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahq
kvaimrniekmlgealgnpqevgpllntmikgryn

SCOPe Domain Coordinates for d7a1ka_:

Click to download the PDB-style file with coordinates for d7a1ka_.
(The format of our PDB-style files is described here.)

Timeline for d7a1ka_:

  • d7a1ka_ is new in SCOPe 2.08-stable