Lineage for Protein: Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

    has additional subdomain(s) that are not in the common domain
  6. 2842415Protein Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain [418935] (1 species)
    protein contains tandem repeat of two SDR-like modules resembling a dimer commonly found in the family; only the second module retains the coenzyme-binding site

Species:

More info for Protein Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain from c.2.1.2: Tyrosine-dependent oxidoreductases:

  • Protein Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain from c.2.1.2: Tyrosine-dependent oxidoreductases is new in SCOPe 2.08-stable