Lineage for d7orea_ (7ore A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2979887Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2979888Species Human (Homo sapiens) [TaxId:9606] [56138] (50 PDB entries)
  8. 2979906Domain d7orea_: 7ore A: [418589]
    automated match to d7cmla_
    complexed with 0ei, edo

Details for d7orea_

PDB Entry: 7ore (more details), 2.18 Å

PDB Description: crystal structure of jnk3 in complex with light-activated covalent inhibitor mr-ii-249 with both non-covalent and covalent binding modes (compound 4)
PDB Compounds: (A:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d7orea_:

Sequence, based on SEQRES records: (download)

>d7orea_ d.144.1.7 (A:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
vdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqt
hakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldh
ermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpy
vvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpc
pefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvid
pakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmnse

Sequence, based on observed residues (ATOM records): (download)

>d7orea_ d.144.1.7 (A:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
vdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqt
hakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldh
ermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpy
vvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpc
pefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvid
pakrisvddalqhpyinvwydpaeveapplderehtieewkeliykevmnse

SCOPe Domain Coordinates for d7orea_:

Click to download the PDB-style file with coordinates for d7orea_.
(The format of our PDB-style files is described here.)

Timeline for d7orea_:

  • d7orea_ is new in SCOPe 2.08-stable