SCOPe 2.08: Domain d7e0tb_: 7e0t B:

Lineage for d7e0tb_ (7e0t B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
   multihelical; bundle, contains interrupted helices

4. Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families)
   contains heme-dependent enzymes

5. Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 proteins)
   Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)

6. Protein automated matches [190585] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187592] (52 PDB entries)

8. Domain d7e0tb_: 7e0t B: [418005]
   automated match to d5wmxa_
   complexed with hem, hu9

Details for d7e0tb_

PDB Entry: 7e0t, 2.14 Å

PDB Description: crystal structure of human indoleamine 2,3-dioxygenagse 1 (hido1) complexed with (1r,2s)-2-(((5-bromo-1h-indazol-4-yl)amino)methyl) cyclohexan-1-ol (36)

PDB Compounds: (B:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d7e0tb_:

Sequence, based on SEQRES records:

>d7e0tb_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedp
skleakgtggtdlmnflktvrstteksll

Sequence, based on observed residues (ATOM records):

>d7e0tb_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqggtdlmnflkt
vrstteksll

Timeline for d7e0tb_:

• d7e0tb_ is new in SCOPe 2.08-stable