SCOPe 2.07: Domain d1dewb_: 1dew B:

Lineage for d1dewb_ (1dew B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.151: DNase I-like [56218] (1 superfamily)
   contains beta-sandwich; duplication of alpha+beta motif

4. Superfamily d.151.1: DNase I-like [56219] (4 families)

5. Family d.151.1.1: DNase I-like [56220] (7 proteins)

6. Protein DNA repair endonuclease Hap1 [56223] (1 species)
   Major apurinic/apyrimidinic endonuclease APE1

7. Species Human (Homo sapiens) [TaxId:9606] [56224] (15 PDB entries)

8. Domain d1dewb_: 1dew B: [41787]
   protein/DNA complex; complexed with so4

Details for d1dewb_

PDB Entry: 1dew, 2.65 Å

PDB Description: crystal structure of human ape1 bound to abasic dna

PDB Compounds: (B:) major apurinic/apyrimidinic endonuclease

SCOPe Domain Sequences for d1dewb_:

Sequence; same for both SEQRES and ATOM records:

>d1dewb_ d.151.1.1 (B:) DNA repair endonuclease Hap1 {Human (Homo sapiens) [TaxId: 9606]}
egpalyedppdhktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilclqetkc
senklpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdqegrviv
aefdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeid
lrnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvg
wrldyfllshsllpalcdskirskalgsdhcpitlylal

Timeline for d1dewb_:

• d1dewb_ first appeared (with stable ids) in SCOP 1.55
  
• d1dewb_ appears in SCOPe 2.06
  
• d1dewb_ appears in the current release, SCOPe 2.08