SCOP 1.59: Domain d1e8xa4: 1e8x A:726-1092

Lineage for d1e8xa4 (1e8x A:726-1092)

1. Root: SCOP 1.59

2. Class d: Alpha and beta proteins (a+b) [53931] (208 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)

5. Family d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain [56171] (1 protein)

6. Protein Phoshoinositide 3-kinase (PI3K), catalytic domain [56172] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [56173] (5 PDB entries)

8. Domain d1e8xa4: 1e8x A:726-1092 [41711]
   Other proteins in same PDB: d1e8xa1, d1e8xa2, d1e8xa3

Details for d1e8xa4

PDB Entry: 1e8x, 2.2 Å

PDB Description: structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling

SCOP Domain Sequences for d1e8xa4:

Sequence, based on SEQRES records:

>d1e8xa4 d.144.1.4 (A:726-1092) Phoshoinositide 3-kinase (PI3K), catalytic domain {Pig (Sus scrofa)}
tamlhdftqqvqvidmlqkvtidikslsaekydvssqvisqlkqklenlqnlnlpqsfrv
pydpglkagalviekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlshwlkekcpieekfqaaverfvyscagycvatfvlgigdrhndnimisetgnlfhidf
ghilgnyksflginkervpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtn
lliilfsmmlmtgmpqltskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfn
wflhlvl

Sequence, based on observed residues (ATOM records):

>d1e8xa4 d.144.1.4 (A:726-1092) Phoshoinositide 3-kinase (PI3K), catalytic domain {Pig (Sus scrofa)}
tamlhdftqqvqvidmlqkvtidikslsaekydvssqvisqlkqklenlqnlnlpqsfrv
pydpglkagalviekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlshwlkekcpieekfqaaverfvyscagycvatfvlgigdrhndnimisetgnlfhidf
ghvpfvltpdflfvmgtsgkktslhfqkfqdvcvkaylalrhhtnlliilfsmmlmtgmp
qltskedieyirdaltvgkseedakkyfldqievcrdkgwtvqfnwflhlvl

Timeline for d1e8xa4:

• d1e8xa4 first appeared (with stable ids) in SCOP 1.55
  
• d1e8xa4 appears in SCOP 1.57
  
• d1e8xa4 appears in SCOP 1.61
  
• d1e8xa4 appears in the current release, SCOPe 2.08