SCOP 1.57: Domain d1fmk_3: 1fmk 249-533

Lineage for d1fmk_3 (1fmk 249-533)

1. Root: SCOP 1.57

2. Class d: Alpha and beta proteins (a+b) [53931] (194 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)

5. Family d.144.1.2: Tyrosine kinase [56150] (9 proteins)

6. Protein c-src tyrosine kinase [56155] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56156] (2 PDB entries)

8. Domain d1fmk_3: 1fmk 249-533 [41690]
   Other proteins in same PDB: d1fmk_1, d1fmk_2

Details for d1fmk_3

PDB Entry: 1fmk, 1.5 Å

PDB Description: crystal structure of human tyrosine-protein kinase c-src

SCOP Domain Sequences for d1fmk_3:

Sequence, based on SEQRES records:

>d1fmk_3 d.144.1.2 (249-533) c-src tyrosine kinase {Human (Homo sapiens)}
kpqtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeafl
qeaqvmkklrheklvqlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaa
qiasgmayvermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikw
tapeaalygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecp
eslhdlmcqcwrkepeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d1fmk_3 d.144.1.2 (249-533) c-src tyrosine kinase {Human (Homo sapiens)}
kpqtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeafl
qeaqvmkklrheklvqlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaa
qiasgmayvermnyvhrdlraanilvgenlvckvadfglarfpikwtapeaalygrftik
sdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrke
peerptfeylqafledyftstepqyqpgenl

Timeline for d1fmk_3:

• d1fmk_3 first appeared (with stable ids) in SCOP 1.55
  
• d1fmk_3 appears in SCOP 1.59
  
• d1fmk_3 appears in the current release, SCOPe 2.08, called d1fmka3