SCOPe 2.05: Domain d1howa_: 1how A:

Lineage for d1howa_ (1how A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Sky1p [56148] (1 species)
   CMGC group; Clk subfamily; serine/threonine kinase

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56149] (5 PDB entries)

8. Domain d1howa_: 1how A: [41679]
   residues 305-538 were deleted and replaced with Val-Asp
   complexed with edo, so4

Details for d1howa_

PDB Entry: 1how, 2.1 Å

PDB Description: the x-ray crystal structure of sky1p, an sr protein kinase in yeast

PDB Compounds: (A:) serine/threonine-protein kinase ymr216c

SCOPe Domain Sequences for d1howa_:

Sequence, based on SEQRES records:

>d1howa_ d.144.1.7 (A:) Sky1p {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
fhpafkgepykdaryilvrklgwghfstvwlakdmvnnthvamkivrgdkvyteaaedei
kllqrvndadntkedsmganhilklldhfnhkgpngvhvvmvfevlgenllalikkyehr
gipliyvkqiskqlllgldymhrrcgiihtdikpenvlmeivdspenliqikiadlgnac
wydehytnsiqtreyrspevllgapwgcgadiwstaclifelitgdflfepdeghsytkd
ddhiaqiiellgelpsyllrngkytrtffnsrgllrnisklkfwpledvltekykfskde
akeisdflspmlqldprkradagglvnhpwlkdtlgmeeirvpdrelygsgsdipgwfee
vr

Sequence, based on observed residues (ATOM records):

>d1howa_ d.144.1.7 (A:) Sky1p {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
fhpafkgepykdaryilvrklgwghfstvwlakdmvnnthvamkivrgdkvyteaaedei
kllqrvndadntkedsmganhilklldhfnhkgpngvhvvmvfevlgenllalikkyehr
gipliyvkqiskqlllgldymhrrcgiihtdikpenvlmeivdspenliqikiadlgnac
wydehytnsiqtreyrspevllgapwgcgadiwstaclifelitgdflfepddddhiaqi
iellgelpsyllrngkytrtffsklkfwpledvltekykfskdeakeisdflspmlqldp
rkradagglvnhpwlkdtlgmeeirvpdrelygsgsdipgwfeevr

Timeline for d1howa_:

• d1howa_ first appeared (with stable ids) in SCOP 1.55
  
• d1howa_ appears in SCOPe 2.04
  
• d1howa_ appears in SCOPe 2.06
  
• d1howa_ appears in the current release, SCOPe 2.08