SCOPe 2.06: Domain d1bx6a_: 1bx6 A:

Lineage for d1bx6a_ (1bx6 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein cAMP-dependent PK, catalytic subunit [56116] (5 species)
   AGC group; PKA subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56119] (30 PDB entries)

8. Domain d1bx6a_: 1bx6 A: [41631]
   complexed with ba1

Details for d1bx6a_

PDB Entry: 1bx6, 2.1 Å

PDB Description: crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of camp-dependent protein kinase

PDB Compounds: (A:) cAMP-DEPENDENT PROTEIN KINASE

SCOPe Domain Sequences for d1bx6a_:

Sequence; same for both SEQRES and ATOM records:

>d1bx6a_ d.144.1.7 (A:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
qesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyam
kildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfsh
lrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrv
kgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekiv
sgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkve
apfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

Timeline for d1bx6a_:

• d1bx6a_ first appeared (with stable ids) in SCOP 1.55, called d1bx6__
  
• d1bx6a_ appears in SCOPe 2.05
  
• d1bx6a_ appears in SCOPe 2.07
  
• d1bx6a_ appears in the current release, SCOPe 2.08