SCOP 1.61: Domain d1bi7a_: 1bi7 A:

Lineage for d1bi7a_ (1bi7 A:)

1. Root: SCOP 1.61

2. Class d: Alpha and beta proteins (a+b) [53931] (212 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)

5. Family d.144.1.1: Serine/threonin kinases [56113] (18 proteins)

6. Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56115] (38 PDB entries)

8. Domain d1bi7a_: 1bi7 A: [41619]
   Other proteins in same PDB: d1bi7b_

Details for d1bi7a_

PDB Entry: 1bi7, 3.4 Å

PDB Description: mechanism of g1 cyclin dependent kinase inhibition from the structure of the cdk6-p16ink4a tumor suppressor complex

SCOP Domain Sequences for d1bi7a_:

Sequence, based on SEQRES records:

>d1bi7a_ d.144.1.1 (A:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
dqqyecvaeigegaygkvfkardlknggrfvalkrvrvqtgeegmplstirevavlrhle
tfehpnvvrlfdvctvsrtdretkltlvfehvdqdlttyldkvpepgvptetikdmmfql
lrgldflhshrvvhrdlkpqnilvtssgqikladfglariysfqmaltsvvvtlwyrape
vllqssyatpvdlwsvgcifaemfrrkplfrgssdvdqlgkildviglpgeedwprdval
prqafhsksaqpiekfvtdidelgkdlllkcltfnpakrisaysalshpyfq

Sequence, based on observed residues (ATOM records):

>d1bi7a_ d.144.1.1 (A:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
dqqyecvaeigegaygkvfkardlknggrfvalkrvrvqehpnvvrlfdvctvsrtdret
kltlvfehvdqdlttyldkvpepgvptetikdmmfqllrgldflhshrvvhrdlkpqnil
vtssgqikladfglariysfqmaltsvvvtlwyrapevllqssyatpvdlwsvgcifaem
frrkplfrgssdvdqlgkildviglpgeedwprdvalprqafhsksaqpiekfvtdidel
gkdlllkcltfnpakrisaysalshpyfq

Timeline for d1bi7a_:

• d1bi7a_ first appeared (with stable ids) in SCOP 1.55
  
• d1bi7a_ appears in SCOP 1.59
  
• d1bi7a_ appears in SCOP 1.63
  
• d1bi7a_ appears in the current release, SCOPe 2.08