SCOP 1.63: Domain d1fvvc_: 1fvv C:

Lineage for d1fvvc_ (1fvv C:)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)

6. Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)

8. Domain d1fvvc_: 1fvv C: [41616]
   Other proteins in same PDB: d1fvvb1, d1fvvb2, d1fvvd1, d1fvvd2
   complexed with 107

Details for d1fvvc_

PDB Entry: 1fvv, 2.8 Å

PDB Description: the structure of cdk2/cyclin a in complex with an oxindole inhibitor

SCOP Domain Sequences for d1fvvc_:

Sequence; same for both SEQRES and ATOM records:

>d1fvvc_ d.144.1.1 (C:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d1fvvc_:

• d1fvvc_ first appeared (with stable ids) in SCOP 1.55
  
• d1fvvc_ appears in SCOP 1.61
  
• d1fvvc_ appears in SCOP 1.65
  
• d1fvvc_ appears in the current release, SCOPe 2.08