Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins) members organized in the groups and subfamiles specified by the comments |
Protein Cyclin-dependent PK, CDK2 [88855] (2 species) CMGC group; CDKs subfamily; serine/threonine kinase |
Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries) Uniprot P24941 |
Domain d1dm2a_: 1dm2 A: [41598] complexed with edo, hmd |
PDB Entry: 1dm2 (more details), 2.1 Å
SCOPe Domain Sequences for d1dm2a_:
Sequence, based on SEQRES records: (download)
>d1dm2a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]} menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
>d1dm2a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]} menfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldv ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk pqnllintegaikladfglvtlwyrapeillgckyystavdiwslgcifaemvtrralfp gdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrslls qmlhydpnkrisakaalahpffqdvtkpvphlrl
Timeline for d1dm2a_: