Class b: All beta proteins [48724] (180 folds) |
Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies) one turn of helix is made by two pairs of antiparallel strands linked with short turns has appearance of a sandwich of distinct architecture and jelly-roll topology |
Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold |
Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins) Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801 Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811) |
Protein KDM5B (JARID1B or PLU1) core [419085] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [419582] (14 PDB entries) |
Domain d5lw9a1: 5lw9 A:26-622 [415048] Other proteins in same PDB: d5lw9a2, d5lw9a3 automated match to d5a1fa1 complexed with 5uj, dms, edo, mn, zn |
PDB Entry: 5lw9 (more details), 2.3 Å
SCOPe Domain Sequences for d5lw9a1:
Sequence, based on SEQRES records: (download)
>d5lw9a1 b.82.2.14 (A:26-622) KDM5B (JARID1B or PLU1) core {Human (Homo sapiens) [TaxId: 9606]} flpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhftp riqrlneleaqtrvklggggardytlrtfgemadafksdyfnmpvhmvptelvekefwrl vstieedvtveygadiaskefgsgfpvrdgkiklspeeeeyldsgwnlnnmpvmeqsvla hitadicgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenv mkklapelfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqg fnfaeavnfctvdwlplgrqcvehyrllh
>d5lw9a1 b.82.2.14 (A:26-622) KDM5B (JARID1B or PLU1) core {Human (Homo sapiens) [TaxId: 9606]} flpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhftp riqrlneleaqtrvkardytlrtfgemadafksdyfnmpvhmvptelvekefwrlvstie edvtveygadiaskefgsgfpvrdgiklspeeeeyldsgwnlnnmpvmeqsvlahitadi cgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkklap elfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfaea vnfctvdwlplgrqcvehyrllh
Timeline for d5lw9a1: