SCOPe 2.08: Domain d4d2va1: 4d2v A:1-333

Lineage for d4d2va1 (4d2v A:1-333)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4d2va1: 4d2v A:1-333 [413753]
   Other proteins in same PDB: d4d2va2
   automated match to d4ixpa_
   complexed with 45r

Details for d4d2va1

PDB Entry: 4d2v, 2.45 Å

PDB Description: structure of melk in complex with inhibitors

PDB Compounds: (A:) maternal embryonic leucine zipper kinase

SCOPe Domain Sequences for d4d2va1:

Sequence, based on SEQRES records:

>d4d2va1 d.144.1.0 (A:1-333) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkdydellkyyelhetigtggfakvklachiltgemvaikimdkntlgsdlprikteiea
lknlrhqhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsav
ayvhsqgyahrdlkpenllfdeyhklklidfglcakpkgnkdyhlqaccgalayaapeli
qgksylgseadvwsmgillyvlmcgflpfdddtaaalvakimrgkydvpkwlspssilll
qqmlqvdpkkrismknllnhpwimqdynypvewqsknpfihldddcvtelsvhhrnnrqt
medlislwqydhltatyllllakkargkpvrlr

Sequence, based on observed residues (ATOM records):

>d4d2va1 d.144.1.0 (A:1-333) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkdydellkyyelhetigtggfakvklachiltgemvaikimdkntdlprikteiealkn
lrhqhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsavayv
hsqgyahrdlkpenllfdeyhklklidfglcgalayaapeliqgkgseadvwsmgillyv
lmcgflpfdddtaaalvakimrgkydvpkwlspssilllqqmlqvdpkkrismknllnhp
wimqdynypvewqsknpfihldddcvtelsvhhrnnrqtmedlislwqydhltatyllll
akkargkpvrlr

Timeline for d4d2va1:

• d4d2va1 is new in SCOPe 2.08-stable