SCOP 1.65: Domain d1boa_2: 1boa 110-374,449-478

Lineage for d1boa_2 (1boa 110-374,449-478)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.127: Creatinase/aminopeptidase [55919] (1 superfamily)
   duplication: composed of two very similar alpha+beta folds

4. Superfamily d.127.1: Creatinase/aminopeptidase [55920] (1 family)

5. Family d.127.1.1: Creatinase/aminopeptidase [55921] (3 proteins)

6. Protein Methionine aminopeptidase [55924] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55927] (4 PDB entries)
   methionine aminopeptidase 2 contains insert domain with a circularly permuted "winged helix" fold

8. Domain d1boa_2: 1boa 110-374,449-478 [41163]
   Other proteins in same PDB: d1boa_1
   complexed with co, fum

Details for d1boa_2

PDB Entry: 1boa, 1.8 Å

PDB Description: human methionine aminopeptidase 2 complexed with angiogenesis inhibitor fumagillin

SCOP Domain Sequences for d1boa_2:

Sequence, based on SEQRES records:

>d1boa_2 d.127.1.1 (110-374,449-478) Methionine aminopeptidase {Human (Homo sapiens)}
kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikg
geatrmeegevyaietfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Sequence, based on observed residues (ATOM records):

>d1boa_2 d.127.1.1 (110-374,449-478) Methionine aminopeptidase {Human (Homo sapiens)}
kvqtdppsvpicdlypngvfpkgqeceypekkaldqaseeiwndfreaaeahrqvrkyvm
swikpgmtmieicekledcsrklikenglnaglafptgcslnncaahytpnagdttvlqy
ddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikcagidvrlcdvgeai
qevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikggeatrmeegevyaie
tfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Timeline for d1boa_2:

• d1boa_2 first appeared (with stable ids) in SCOP 1.55
  
• d1boa_2 appears in SCOP 1.63
  
• d1boa_2 appears in SCOP 1.67
  
• d1boa_2 appears in the current release, SCOPe 2.08, called d1boaa2