SCOPe 2.08: Domain d1b59a2: 1b59 A:110-374,A:449-478

Lineage for d1b59a2 (1b59 A:110-374,A:449-478)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.127: Creatinase/aminopeptidase [55919] (1 superfamily)
   duplication: composed of two very similar alpha+beta folds

4. Superfamily d.127.1: Creatinase/aminopeptidase [55920] (2 families)

5. Family d.127.1.1: Creatinase/aminopeptidase [55921] (4 proteins)

6. Protein Methionine aminopeptidase [55924] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55927] (18 PDB entries)
   Uniprot P50579 110-478
   methionine aminopeptidase 2 contains insert domain with a circularly permuted "winged helix" fold

8. Domain d1b59a2: 1b59 A:110-374,A:449-478 [41162]
   Other proteins in same PDB: d1b59a1
   complexed with co, ova

Details for d1b59a2

PDB Entry: 1b59, 1.8 Å

PDB Description: complex of human methionine aminopeptidase-2 complexed with ovalicin

PDB Compounds: (A:) protein (methionine aminopeptidase)

SCOPe Domain Sequences for d1b59a2:

Sequence, based on SEQRES records:

>d1b59a2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens) [TaxId: 9606]}
kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkg
geatrmeegevyaietfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Sequence, based on observed residues (ATOM records):

>d1b59a2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens) [TaxId: 9606]}
kvqtdppsvpicdlypngvfpkgqeceypeekkaldqaseeiwndfreaaeahrqvrkyv
mswikpgmtmieicekledcsrklikenglnaglafptgcslnncaahytpnagdttvlq
yddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikcagidvrlcdvgea
iqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkggeatrmeegevyai
etfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Timeline for d1b59a2:

• d1b59a2 first appeared (with stable ids) in SCOP 1.55
  
• d1b59a2 appears in SCOPe 2.07