SCOPe 2.08: Domain d1yeta_: 1yet A:

Lineage for d1yeta_ (1yet A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein HSP90 [55876] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55878] (189 PDB entries)
   Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223

8. Domain d1yeta_: 1yet A: [41102]
   complexed with gdm

Details for d1yeta_

PDB Entry: 1yet, 1.9 Å

PDB Description: geldanamycin bound to the hsp90 geldanamycin-binding domain

PDB Compounds: (A:) heat shock protein 90

SCOPe Domain Sequences for d1yeta_:

Sequence; same for both SEQRES and ATOM records:

>d1yeta_ d.122.1.1 (A:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
pmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryetltdpskl
dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
kedqteyleerrikeivkkhsqfigypitlfve

Timeline for d1yeta_:

• d1yeta_ first appeared (with stable ids) in SCOP 1.55, called d1yet__
  
• d1yeta_ appears in SCOPe 2.07