SCOPe 2.07: Domain d1tisa_: 1tis A:

Lineage for d1tisa_ (1tis A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Bacteriophage T4 [TaxId:10665] [55837] (1 PDB entry)

8. Domain d1tisa_: 1tis A: [41040]
   complexed with po4

Details for d1tisa_

PDB Entry: 1tis, 2.7 Å

PDB Description: crystal structure of thymidylate synthase from t4 phage

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1tisa_:

Sequence; same for both SEQRES and ATOM records:

>d1tisa_ d.117.1.1 (A:) Thymidylate synthase {Bacteriophage T4 [TaxId: 10665]}
mkqyqdlikdifengyetddrtgtgtialfgsklrwdltkgfpavttkklawkaciaeli
wflsgstnvndlrliqhdsliqgktvwdenyenqakdlgyhsgelgpiygkqwrdfggvd
qiievidrikklpndrrqivsawnpaelkymalppchmfyqfnvrngyldlqwyqrsvdv
flglpfniasyatlvhivakmcnlipgdlifsggnthiymnhveqckeilrrepkelcel
visglpykfrylstkeqlkyvlklrpkdfvlnnyvshppikgkmav

Timeline for d1tisa_:

• d1tisa_ first appeared (with stable ids) in SCOP 1.55, called d1tis__
  
• d1tisa_ appears in SCOPe 2.06
  
• d1tisa_ appears in the current release, SCOPe 2.08