SCOPe 2.07: Domain d2tdda_: 2tdd A:

Lineage for d2tdda_ (2tdd A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Lactobacillus casei [TaxId:1582] [55835] (51 PDB entries)

8. Domain d2tdda_: 2tdd A: [41021]
   complexed with thf, ufp

Details for d2tdda_

PDB Entry: 2tdd, 2.7 Å

PDB Description: structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d2tdda_:

Sequence; same for both SEQRES and ATOM records:

>d2tdda_ d.117.1.1 (A:) Thymidylate synthase {Lactobacillus casei [TaxId: 1582]}
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapva

Timeline for d2tdda_:

• d2tdda_ first appeared (with stable ids) in SCOP 1.55, called d2tdd__
  
• d2tdda_ appears in SCOPe 2.06
  
• d2tdda_ appears in the current release, SCOPe 2.08