Lineage for d1tlsa1 (1tls A:2-264)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2212073Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2212074Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2212075Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
  6. 2212113Protein Thymidylate synthase [55833] (7 species)
  7. 2212128Species Escherichia coli [TaxId:562] [55834] (67 PDB entries)
  8. 2212225Domain d1tlsa1: 1tls A:2-264 [40982]
    Other proteins in same PDB: d1tlsa2, d1tlsb2
    complexed with c2f, ufp

Details for d1tlsa1

PDB Entry: 1tls (more details), 2.6 Å

PDB Description: thymidylate synthase ternary complex with fdump and methylenetetrahydrofolate
PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1tlsa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1tlsa1 d.117.1.1 (A:2-264) Thymidylate synthase {Escherichia coli [TaxId: 562]}
kqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihellw
flqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlkn
dpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfniasy
allvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesifd
yrfedfeiegydphpgikapvai

SCOPe Domain Coordinates for d1tlsa1:

Click to download the PDB-style file with coordinates for d1tlsa1.
(The format of our PDB-style files is described here.)

Timeline for d1tlsa1:

View in 3D
Domains from same chain:
(mouse over for more information)
d1tlsa2