SCOPe 2.08: Domain d4z5rw_: 4z5r W:

Lineage for d4z5rw_ (4z5r W:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein automated matches [190119] (24 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188740] (709 PDB entries)

8. Domain d4z5rw_: 4z5r W: [409748]
   Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rd_, d4z5re_, d4z5rf_, d4z5rg_, d4z5rh_, d4z5ri_, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rn_, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5rx_, d4z5ry_
   automated match to d6shgh_
   complexed with so4

Details for d4z5rw_

PDB Entry: 4z5r, 3 Å

PDB Description: rontalizumab fab bound to interferon-a2

PDB Compounds: (W:) anti-IFN-a antibody rontalizumab heavy chain modules VH and CH1 (Fab)

SCOPe Domain Sequences for d4z5rw_:

Sequence, based on SEQRES records:

>d4z5rw_ b.1.1.1 (W:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
evqlvesggglvqpggslrlscatsgytfteyiihwvrqapgkglewvasinpdyditny
nqrfkgrftisldkskrtaylqmnslraedtavyycaswisdffdywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

Sequence, based on observed residues (ATOM records):

>d4z5rw_ b.1.1.1 (W:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
evqlvesggglvqpggslrlscatsgytfteyiihwvrqapgkglewvasinpdyditny
nqrfkgrftisldkskrtaylqmnslraedtavyycaswisdffdywgqgtlvtvssast
kgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

Timeline for d4z5rw_:

• d4z5rw_ is new in SCOPe 2.08-stable