SCOPe 2.05: Domain d1tsna_: 1tsn A:

Lineage for d1tsna_ (1tsn A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (64 PDB entries)

8. Domain d1tsna_: 1tsn A: [40970]
   complexed with c2f, po4, ufp

Details for d1tsna_

PDB Entry: 1tsn, 2.2 Å

PDB Description: thymidylate synthase ternary complex with fdump and methylenetetrahydrofolate

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1tsna_:

Sequence; same for both SEQRES and ATOM records:

>d1tsna_ d.117.1.1 (A:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d1tsna_:

• d1tsna_ first appeared (with stable ids) in SCOP 1.55, called d1tsn__
  
• d1tsna_ appears in SCOPe 2.04
  
• d1tsna_ is called d1tsna1 in SCOPe 2.06
  
• d1tsna_ appears in the current release, SCOPe 2.08, called d1tsna1