Lineage for d1kcea1 (1kce A:2-264)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2212073Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2212074Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2212075Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
  6. 2212113Protein Thymidylate synthase [55833] (7 species)
  7. 2212128Species Escherichia coli [TaxId:562] [55834] (67 PDB entries)
  8. 2212164Domain d1kcea1: 1kce A:2-264 [40944]
    Other proteins in same PDB: d1kcea2, d1kceb2
    complexed with cb3, ump; mutant

Details for d1kcea1

PDB Entry: 1kce (more details), 2 Å

PDB Description: e. coli thymidylate synthase mutant e58q in complex with cb3717 and 2'-deoxyuridine 5'-monophosphate (dump)
PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1kcea1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1kcea1 d.117.1.1 (A:2-264) Thymidylate synthase {Escherichia coli [TaxId: 562]}
kqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihellw
flqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlkn
dpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfniasy
allvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesifd
yrfedfeiegydphpgikapvai

SCOPe Domain Coordinates for d1kcea1:

Click to download the PDB-style file with coordinates for d1kcea1.
(The format of our PDB-style files is described here.)

Timeline for d1kcea1:

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d1kcea2