SCOPe 2.06: Domain d1tlcb_: 1tlc B:

Lineage for d1tlcb_ (1tlc B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (67 PDB entries)

8. Domain d1tlcb_: 1tlc B: [40943]
   complexed with dgp, f89

Details for d1tlcb_

PDB Entry: 1tlc, 2.1 Å

PDB Description: thymidylate synthase complexed with dgmp and folate analog 1843u89

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d1tlcb_:

Sequence; same for both SEQRES and ATOM records:

>d1tlcb_ d.117.1.1 (B:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d1tlcb_:

• d1tlcb_ first appeared (with stable ids) in SCOP 1.55
  
• d1tlcb_ appears in SCOPe 2.05
  
• d1tlcb_ appears in SCOPe 2.07
  
• d1tlcb_ appears in the current release, SCOPe 2.08