SCOPe 2.08: Domain d4jk1x3: 4jk1 X:6-448

Lineage for d4jk1x3 (4jk1 X:6-448)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.177: Sigma2 domain of RNA polymerase sigma factors [88945] (1 superfamily)
   multihelical; consists of a conserved 4-helical core and a variable insert subdomain

4. Superfamily a.177.1: Sigma2 domain of RNA polymerase sigma factors [88946] (2 families)

5. Family a.177.1.1: Sigma2 domain of RNA polymerase sigma factors [88947] (6 proteins)

6. Protein Sigma70 [88948] (2 species)

7. Species Escherichia coli [TaxId:562] [48332] (2 PDB entries)
   Uniprot P00579 546-613

8. Domain d4jk1x3: 4jk1 X:6-448 [409054]
   Other proteins in same PDB: d4jk1x1, d4jk1x2, d4jk1y1, d4jk1y2
   protein/DNA complex; complexed with g4p, zn
   has additional subdomain(s) that are not in the common domain

Details for d4jk1x3

PDB Entry: 4jk1, 3.9 Å

PDB Description: X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp)

PDB Compounds: (X:) Escherichia coli RNA polymerase sigma70 subunit

SCOPe Domain Sequences for d4jk1x3:

Sequence, based on SEQRES records:

>d4jk1x3 a.177.1.1 (X:6-448) Sigma70 {Escherichia coli [TaxId: 562]}
qsqlkllvtrgkeqgyltyaevndhlpedivdsdqiediiqmindmgiqvmeeapdaddl
mlaentadedaaeaaaqvlssveseigrttdpvrmymremgtvelltregeidiakried
ginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvdpnaeedlaptathvgsel
sqedldddededeedgdddsadddnsidpelarekfaelraqyvvtrdtikakgrshata
qeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitl
ftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrm
sigeakarrakkemveanlrlvisiakkytnrglqfldliqegniglmkavdkfeyrrgy
kfstyatwwirqaitrsiadqar

Sequence, based on observed residues (ATOM records):

>d4jk1x3 a.177.1.1 (X:6-448) Sigma70 {Escherichia coli [TaxId: 562]}
qsqlkllvtrgkeqgyltyaevndhlpedivdsdqiediiqmindmgiqvmeeapdaddt
dpvrmymremgtvelltregeidiakriedginqvqcsvaeypeaitylleqydrveaei
dpelarekfaelraqyvvtrdtikakgrshataqeeilklsevfkqfrlvpkqfdylvns
mrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhd
vseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveanlrlvisiak
kytnrglqfldliqegniglmkavdkfeyrrgykfstyatwwirqaitrsiadqar

Timeline for d4jk1x3:

• d4jk1x3 is new in SCOPe 2.08-stable