Lineage for d3t3me_ (3t3m E:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2742100Protein automated matches [190119] (24 species)
    not a true protein
  7. 2744177Species Mouse (Mus musculus) [TaxId:10090] [186842] (622 PDB entries)
  8. 2744707Domain d3t3me_: 3t3m E: [408679]
    Other proteins in same PDB: d3t3ma_, d3t3mc_, d3t3mf1, d3t3mf2, d3t3ml1, d3t3ml2
    automated match to d6shgh_
    complexed with ca, cl, nag, rc2, so4

Details for d3t3me_

PDB Entry: 3t3m (more details), 2.6 Å

PDB Description: a novel high affinity integrin alphaiibbeta3 receptor antagonist that unexpectedly displaces mg2+ from the beta3 midas
PDB Compounds: (E:) monoclonal antibody 10e5 heavy chain

SCOPe Domain Sequences for d3t3me_:

Sequence, based on SEQRES records: (download)

>d3t3me_ b.1.1.1 (E:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
evqlqqsgaelvkpgasvklsctasgfnikdtyvhwvkqrpeqglewigridpangytky
dpkfqgkatitadtssntaylqlssltsedtavyycvrplydyyamdywgqgtsvtvssa
kttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdl
ytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

Sequence, based on observed residues (ATOM records): (download)

>d3t3me_ b.1.1.1 (E:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
evqlqqsgaelvkpgasvklsctasgfnikdtyvhwvkqrpeqglewigridpangytky
dpkfqgkatitadtssntaylqlssltsedtavyycvrplydyyamdywgqgtsvtvssa
kttapsvyplapvcssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlss
svtvtsstwpsqsitcnvahpasstkvdkkiepr

SCOPe Domain Coordinates for d3t3me_:

Click to download the PDB-style file with coordinates for d3t3me_.
(The format of our PDB-style files is described here.)

Timeline for d3t3me_:

  • d3t3me_ is new in SCOPe 2.08-stable