SCOPe 2.08: Domain d1c0gs_: 1c0g S:

Lineage for d1c0gs_ (1c0g S:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.109: Gelsolin-like [55752] (3 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families)

5. Family d.109.1.1: Gelsolin-like [55754] (5 proteins)

6. Protein Gelsolin [55759] (2 species)
   consists of six similar domains

7. Species Human (Homo sapiens) [TaxId:9606] [55761] (47 PDB entries)
   Uniprot P20065 55-179

8. Domain d1c0gs_: 1c0g S: [40848]
   Other proteins in same PDB: d1c0ga1, d1c0ga2
   domain 1
   complexed with atp, ca; mutant

Details for d1c0gs_

PDB Entry: 1c0g, 2 Å

PDB Description: crystal structure of 1:1 complex between gelsolin segment 1 and a dictyostelium/tetrahymena chimera actin (mutant 228: q228k/t229a/a230y/e360h)

PDB Compounds: (S:) protein (gelsolin segment 1)

SCOPe Domain Sequences for d1c0gs_:

Sequence; same for both SEQRES and ATOM records:

>d1c0gs_ d.109.1.1 (S:) Gelsolin {Human (Homo sapiens) [TaxId: 9606]}
mgsvvehpeflkagkepglqiwrvekfdlvpvptclygdfftgdayvilktvqlrngnlq
ydlhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykk
ggvasgf

Timeline for d1c0gs_:

• d1c0gs_ first appeared (with stable ids) in SCOP 1.55
  
• d1c0gs_ appears in SCOPe 2.07