SCOP 1.75: Domain d1vdea2: 1vde A:181-298

Lineage for d1vdea2 (1vde A:181-298)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.95: Homing endonuclease-like [55603] (2 superfamilies)
   alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

4. Superfamily d.95.2: Homing endonucleases [55608] (2 families)

5. Family d.95.2.2: Intein endonuclease [55614] (2 proteins)
   duplication: contains tandem repeat of this fold

6. Protein VMA1-derived endonuclease (VDE) PI-SceI [55615] (1 species)
   homing endonuclease with protein splicing activity

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55616] (7 PDB entries)
   Uniprot P17255 284-737

8. Domain d1vdea2: 1vde A:181-298 [40581]
   Other proteins in same PDB: d1vdea1, d1vdeb1

Details for d1vdea2

PDB Entry: 1vde, 2.4 Å

PDB Description: pi-scei, a homing endonuclease with protein splicing activity

PDB Compounds: (A:) pi-scei

SCOP Domain Sequences for d1vdea2:

Sequence, based on SEQRES records:

>d1vdea2 d.95.2.2 (A:181-298) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pilyendhffdymqkskfhltiegpkvlayllglwigdglsdratfsvdsrdtslmervt
eyaeklnlcaeykdrkepqvaktvnlyskvvrgngirnnlntenplwdaivglgflkd

Sequence, based on observed residues (ATOM records):

>d1vdea2 d.95.2.2 (A:181-298) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pilyendhffdymqkskfhltiegpkvlayllglwigdglsdratfsvdsrdtslmervt
eyaeklnlcaeykdrkepqvaktvnlyskvlntenplwdaivglgflkd

Timeline for d1vdea2:

• d1vdea2 first appeared (with stable ids) in SCOP 1.55
  
• d1vdea2 appears in SCOP 1.73
  
• d1vdea2 appears in SCOPe 2.01
  
• d1vdea2 appears in the current release, SCOPe 2.08