SCOPe 2.08: Domain d1dfaa2: 1dfa A:181-298

Lineage for d1dfaa2 (1dfa A:181-298)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.95: Homing endonuclease-like [55603] (2 superfamilies)
   alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

4. Superfamily d.95.2: Homing endonucleases [55608] (3 families)

5. Family d.95.2.2: Intein endonuclease [55614] (2 proteins)
   duplication: contains tandem repeat of this fold

6. Protein VMA1-derived endonuclease (VDE) PI-SceI [55615] (1 species)
   homing endonuclease with protein splicing activity

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55616] (7 PDB entries)
   Uniprot P17255 284-737

8. Domain d1dfaa2: 1dfa A:181-298 [40575]
   Other proteins in same PDB: d1dfaa1
   fragment; missing more than one-third of the common structure and/or sequence

Details for d1dfaa2

PDB Entry: 1dfa, 2 Å

PDB Description: crystal structure of pi-scei in c2 space group

PDB Compounds: (A:) pi-scei endonuclease

SCOPe Domain Sequences for d1dfaa2:

Sequence, based on SEQRES records:

>d1dfaa2 d.95.2.2 (A:181-298) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pilyendhffdymqkskfhltiegpkvlayllglwigdglsdratfsvdsrdtslmervt
eyaeklnlcaeykdrkepqvaktvnlyskvvrgngirnnlntenplwdaivglgflkd

Sequence, based on observed residues (ATOM records):

>d1dfaa2 d.95.2.2 (A:181-298) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pilyendhffdymqltiegpkvlayllglwigdglsdratfsvdsrdtslmervteyaek
lnlcaeykntenplwdaivglgflkd

Timeline for d1dfaa2:

• d1dfaa2 first appeared (with stable ids) in SCOP 1.55
  
• d1dfaa2 appears in SCOPe 2.07