SCOPe 2.08: Domain d7lrcc_: 7lrc C:

Lineage for d7lrcc_ (7lrc C:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein automated matches [190370] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187208] (27 PDB entries)

8. Domain d7lrcc_: 7lrc C: [405486]
   automated match to d1sojb_
   complexed with mg, mn, x5m

Details for d7lrcc_

PDB Entry: 7lrc, 2.97 Å

PDB Description: cryo-em of the slfn12-pde3a complex: pde3a body refinement

PDB Compounds: (C:) cGMP-inhibited 3',5'-cyclic phosphodiesterase A

SCOPe Domain Sequences for d7lrcc_:

Sequence, based on SEQRES records:

>d7lrcc_ a.211.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kpilapeplvmdnldsimeqlntwnfpifdlvenigrkcgrilsqvsyrlfedmglfeaf
kipirefmnyfhaleigyrdipyhnrihatdvlhavwylttqpipglstvindhgstsds
dsdsgfthghmgyvfsktynvtddkygclsgnipalelmalyvaaamhdydhpgrtnafl
vatsapqavlyndrsvlenhhaaaawnlfmsrpeynflinldhvefkhfrflvieailat
dlkkhfdfvakfngkvnddvgidwtnendrllvcqmcikladingpakckelhlqwtdgi
vnefyeqgdeeaslglpispfmdrsapqlanlqesfishivgplcnsydsaglmpgkwve
dsdesgdtddpeeeeeeapapneeetcennespkkktfkrrkiycqitqhllqnhkmwkk
vieeeqrlagie

Sequence, based on observed residues (ATOM records):

>d7lrcc_ a.211.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kpilapeplvmdnldsimeqlntwnfpifdlvenigrkcgrilsqvsyrlfedmglfeaf
kipirefmnyfhaleigyrdipyhnrihatdvlhavwylttqpipglstvgyvfsktynv
tddkygclsgnipalelmalyvaaamhdydhpgrtnaflvatsapqavlyndrsvlenhh
aaaawnlfmsrpeynflinldhvefkhfrflvieailatdlkkhfdfvakfngkvnddvg
idwtnendrllvcqmcikladingpakckelhlqwtdgivnefyeqgdeeaslglpispf
mdrsapqlanlqesfishivgplcnsydsaglmpgkwverkiycqitqhllqnhkmwkkv
ieeeqrlagie

Timeline for d7lrcc_:

• d7lrcc_ first appeared in SCOPe 2.07