SCOPe 2.07: Domain d7jr6b2: 7jr6 B:76-199

Lineage for d7jr6b2 (7jr6 B:76-199)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.45: GST C-terminal domain-like [47615] (1 superfamily)
   core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix

4. Superfamily a.45.1: GST C-terminal domain-like [47616] (3 families)
   this domains follows the thioredoxin-like N-terminal domain

5. Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (19 proteins)

6. Protein Class sigma GST [81351] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89061] (15 PDB entries)
   Uniprot O60760; synonym: hematopoietic prostaglandin D synthase

8. Domain d7jr6b2: 7jr6 B:76-199 [405337]
   Other proteins in same PDB: d7jr6a1, d7jr6a3, d7jr6b1, d7jr6b3
   automated match to d1pd211
   complexed with gsh, mg, na, vh4

Details for d7jr6b2

PDB Entry: 7jr6, 1.88 Å

PDB Description: h-pdgs complexed with a 2-phenylimidazo[1,2-a]pyridine-6-carboxamide inhibitors

PDB Compounds: (B:) hematopoietic prostaglandin d synthase

SCOPe Domain Sequences for d7jr6b2:

Sequence; same for both SEQRES and ATOM records:

>d7jr6b2 a.45.1.1 (B:76-199) Class sigma GST {Human (Homo sapiens) [TaxId: 9606]}
dlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnelltynaphlmqdldtyl
ggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkvqaipavanwikrrp
qtkl

Timeline for d7jr6b2:

• d7jr6b2 is new in SCOPe 2.07-stable
  
• d7jr6b2 appears in the current release, SCOPe 2.08