SCOPe 2.06: Domain d2abla2: 2abl A:140-237

Lineage for d2abla2 (2abl A:140-237)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Abl tyrosine kinase [55581] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55582] (2 PDB entries)

8. Domain d2abla2: 2abl A:140-237 [40525]
   Other proteins in same PDB: d2abla1

Details for d2abla2

PDB Entry: 2abl, 2.5 Å

PDB Description: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

PDB Compounds: (A:) abl tyrosine kinase

SCOPe Domain Sequences for d2abla2:

Sequence; same for both SEQRES and ATOM records:

>d2abla2 d.93.1.1 (A:140-237) Abl tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
slekhswyhgpvsrnaaeyllssgingsflvresesspgqrsislryegrvyhyrintas
dgklyvssesrfntlaelvhhhstvadglittlhypap

Timeline for d2abla2:

• d2abla2 first appeared (with stable ids) in SCOP 1.55, called d2abl_2
  
• d2abla2 appears in SCOPe 2.05
  
• d2abla2 appears in SCOPe 2.07
  
• d2abla2 appears in the current release, SCOPe 2.08