SCOPe 2.08: Domain d7elxc_: 7elx C:

Lineage for d7elxc_ (7elx C:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoreceptor CTLA-4 (CD152), N-terminal fragment [48939] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48940] (9 PDB entries)

8. Domain d7elxc_: 7elx C: [405247]
   Other proteins in same PDB: d7elxl1, d7elxl2
   automated match to d1i85c_

Details for d7elxc_

PDB Entry: 7elx, 2.14 Å

PDB Description: the crystal structure of ctla-4 and fab

PDB Compounds: (C:) cytotoxic t-lymphocyte protein 4

SCOPe Domain Sequences for d7elxc_:

Sequence, based on SEQRES records:

>d7elxc_ b.1.1.1 (C:) Immunoreceptor CTLA-4 (CD152), N-terminal fragment {Human (Homo sapiens) [TaxId: 9606]}
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvi

Sequence, based on observed residues (ATOM records):

>d7elxc_ b.1.1.1 (C:) Immunoreceptor CTLA-4 (CD152), N-terminal fragment {Human (Homo sapiens) [TaxId: 9606]}
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tfdsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvi

Timeline for d7elxc_:

• d7elxc_ first appeared in SCOPe 2.07