SCOPe 2.05: Domain d1gria3: 1gri A:57-156

Lineage for d1gria3 (1gri A:57-156)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55564] (34 PDB entries)

8. Domain d1gria3: 1gri A:57-156 [40473]
   Other proteins in same PDB: d1gria1, d1gria2, d1grib1, d1grib2

Details for d1gria3

PDB Entry: 1gri, 3.1 Å

PDB Description: grb2

PDB Compounds: (A:) growth factor bound protein 2

SCOPe Domain Sequences for d1gria3:

Sequence; same for both SEQRES and ATOM records:

>d1gria3 d.93.1.1 (A:57-156) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
phpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdgag
kyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpq

Timeline for d1gria3:

• d1gria3 first appeared (with stable ids) in SCOP 1.55
  
• d1gria3 appears in SCOPe 2.04
  
• d1gria3 appears in SCOPe 2.06
  
• d1gria3 appears in the current release, SCOPe 2.08