SCOPe 2.06: Domain d1zfpe_: 1zfp E:

Lineage for d1zfpe_ (1zfp E:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55564] (35 PDB entries)

8. Domain d1zfpe_: 1zfp E: [40465]
   complexed with zn

Details for d1zfpe_

PDB Entry: 1zfp, 1.8 Å

PDB Description: growth factor receptor binding protein sh2 domain complexed with a phosphotyrosyl pentapeptide

PDB Compounds: (E:) growth factor receptor binding protein

SCOPe Domain Sequences for d1zfpe_:

Sequence; same for both SEQRES and ATOM records:

>d1zfpe_ d.93.1.1 (E:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
kphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdga
gkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieq

Timeline for d1zfpe_:

• d1zfpe_ first appeared (with stable ids) in SCOP 1.55
  
• d1zfpe_ appears in SCOPe 2.05
  
• d1zfpe_ appears in SCOPe 2.07
  
• d1zfpe_ appears in the current release, SCOPe 2.08