SCOPe 2.04: Domain d1shda_: 1shd A:

Lineage for d1shda_ (1shd A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein c-src tyrosine kinase [55556] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55557] (46 PDB entries)

8. Domain d1shda_: 1shd A: [40440]

Details for d1shda_

PDB Entry: 1shd, 2 Å

PDB Description: peptide inhibitors of src sh3-sh2-phosphoprotein interactions

PDB Compounds: (A:) c-src tyrosine kinase sh2 domain

SCOPe Domain Sequences for d1shda_:

Sequence, based on SEQRES records:

>d1shda_ d.93.1.1 (A:) c-src tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
siqaeewyfgkitrreserlllnaenprgtflvresettkgayclsvsdfdnakglnvkh
ykirkldsggfyitsrtqfnslqqlvayyskhadglchrlttvcp

Sequence, based on observed residues (ATOM records):

>d1shda_ d.93.1.1 (A:) c-src tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
siqaeewyfgkitrreserlllnaenprgtflvreseayclsvsdfdnakglnvkhykir
kldsggfyitsrtqfnslqqlvayyskhadglchrlttvcp

Timeline for d1shda_:

• d1shda_ first appeared (with stable ids) in SCOP 1.55
  
• d1shda_ appears in SCOPe 2.03
  
• d1shda_ appears in SCOPe 2.05
  
• d1shda_ appears in the current release, SCOPe 2.08