Lineage for d1fbza_ (1fbz A:)

  1. Root: SCOP 1.55
  2. 28523Class d: Alpha and beta proteins (a+b) [53931] (184 folds)
  3. 34525Fold d.93: SH2-like [55549] (1 superfamily)
  4. 34526Superfamily d.93.1: SH2 domain [55550] (1 family) (S)
  5. 34527Family d.93.1.1: SH2 domain [55551] (19 proteins)
  6. 34602Protein p56-lck tyrosine kinase [55552] (1 species)
  7. 34603Species Human (Homo sapiens) [TaxId:9606] [55553] (9 PDB entries)
  8. 34614Domain d1fbza_: 1fbz A: [40422]

Details for d1fbza_

PDB Entry: 1fbz (more details), 2.4 Å

PDB Description: Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity

SCOP Domain Sequences for d1fbza_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fbza_ d.93.1.1 (A:) p56-lck tyrosine kinase {Human (Homo sapiens)}
epepwffknlsrkdaerqllapgnthgsfliresestagsfclsvrdfdqnqgevvkhyk
irnldnggfyispritfpglhelvrhytnasdglctrlsrpcqt

SCOP Domain Coordinates for d1fbza_:

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Timeline for d1fbza_:

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d1fbzb_