SCOPe 2.08: Domain d6x27b_: 6x27 B:

Lineage for d6x27b_ (6x27 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.14: Ribosomal protein S5 domain 2-like [54210] (1 superfamily)
   core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover

4. Superfamily d.14.1: Ribosomal protein S5 domain 2-like [54211] (13 families)

5. Family d.14.1.0: automated matches [191504] (1 protein)
   not a true family

6. Protein automated matches [190826] (23 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189350] (13 PDB entries)

8. Domain d6x27b_: 6x27 B: [403984]
   automated match to d2x36c_
   complexed with 1pe, bo2, gol

Details for d6x27b_

PDB Entry: 6x27, 2.12 Å

PDB Description: lon protease proteolytic domain complexed with bortezomib

PDB Compounds: (B:) lon protease homolog, mitochondrial

SCOPe Domain Sequences for d6x27b_:

Sequence, based on SEQRES records:

>d6x27b_ d.14.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ermydvtppgvvmglawtamggstlfvetslrrpqdkdakgdkdgslevtgqlgevmkes
ariaytfaraflmqhapandylvtshihlhvpegatpkdgpsagctivtallslamgrpv
rqnlamtgevsltgkilpvggikektiaakragvtcivlpaenkkdfydlaafiteglev
hfvehyreifdiafp

Sequence, based on observed residues (ATOM records):

>d6x27b_ d.14.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ermydvtppgvvmglawtamggstlfvetslrrdgslevtgqlgevmkesariaytfara
flmqhapandylvtshihlhvpegatpkdgpsagctivtallslamgrpvrqnlamtgev
sltgkilpvggikektiaakragvtcivlpaenkkdfydlaafiteglevhfvehyreif
diafp

Timeline for d6x27b_:

• d6x27b_ first appeared in SCOPe 2.07