SCOP 1.75: Domain d1i1ip_: 1i1i P:

Lineage for d1i1ip_ (1i1i P:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (17 families)

5. Family d.92.1.5: Neurolysin-like [55505] (4 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein Neurolysin (endopeptidase 24.16, thimet oligopeptidase) [55506] (2 species)
   M3 family member; the thermolysin-like catalytic domain consists of residues 352-674

7. Species Rat (Rattus norvegicus) [TaxId:10116] [55507] (1 PDB entry)

8. Domain d1i1ip_: 1i1i P: [40297]
   complexed with zn

Details for d1i1ip_

PDB Entry: 1i1i, 2.3 Å

PDB Description: neurolysin (endopeptidase 24.16) crystal structure

PDB Compounds: (P:) Neurolysin

SCOP Domain Sequences for d1i1ip_:

Sequence; same for both SEQRES and ATOM records:

>d1i1ip_ d.92.1.5 (P:) Neurolysin (endopeptidase 24.16, thimet oligopeptidase) {Rat (Rattus norvegicus) [TaxId: 10116]}
mssytaagrnvlrwdlspeqiktrteqliaqtkqvydtvgtialkevtyenclqvladie
vtyivertmldfpqhvssdrevraasteadkklsrfdiemsmredvfqrivhlqetcdle
kikpearryleksikmgkrnglhlsehirneiksmkkrmselcidfnknlneddtslvfs
kaelgalpddfidslektdedkykvtlkyphyfpvmkkccvpetrrkmemafhtrckqen
tailqqllplraqvakllgynthadfvlelntakstsrvaaflddlsqklkplgeaeref
ilslkkkeceergfeydgkinawdlhyymtqteelkysvdqeslkeyfpievvtegllsi
yqellglsfeqvpdahvwnksvslytvkdkatgevlgqfyldlypregkynhaacfglqp
gcllpdgsrmmsvaalvvnfsqpvagrpsllrhdevrtyfhefghvmhqicaqtdfarfs
gtnvetdfvevpsqmlenwvwdvdslrklskhykdghpitdelleklvasrlvntglltl
rqivlskvdqslhtnatldaaseyakycteilgvaatpgtnmpatfghlaggydgqyygy
lwsevfsmdmfhscfkkegimnpevgmkyrnlilkpggsldgmdmlqnflqrepnqkafl
msrgl

Timeline for d1i1ip_:

• d1i1ip_ first appeared (with stable ids) in SCOP 1.55
  
• d1i1ip_ appears in SCOP 1.73
  
• d1i1ip_ appears in SCOPe 2.01
  
• d1i1ip_ appears in the current release, SCOPe 2.08