SCOPe 2.08: Domain d6zboe_: 6zbo E:

Lineage for d6zboe_ (6zbo E:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families)
   Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold

5. Family b.82.2.15: proly-4-hydroxylase (P4H, PHD) like [254173] (3 proteins)
   Pfam PF13640; PubMed 16782814

6. Protein automated matches [254532] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [255179] (35 PDB entries)

8. Domain d6zboe_: 6zbo E: [402892]
   automated match to d5lbba_
   complexed with cl, mn, qeq

Details for d6zboe_

PDB Entry: 6zbo, 1.79 Å

PDB Description: hif prolyl hydroxylase 2 (phd2/egln1) in complex with 1-(6- morpholinopyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1h-pyrazol-5-ol (molidustat)

PDB Compounds: (E:) Egl nine homolog 1

SCOPe Domain Sequences for d6zboe_:

Sequence, based on SEQRES records:

>d6zboe_ b.82.2.15 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
palklaleyivpcmnkhgicvvddflgketgqqigdevralhdtgkftdgqlvsqksdss
kdirgdkitwiegkepgcetigllmssmddlirhcngklgsykingrtkamvacypgngt
gyvrhvdnpngdgrcvtciyylnkdwdakvsggilrifpegkaqfadiepkfdrllffws
drrnphevqpayatryaitvwyfdaderarakvkylt

Sequence, based on observed residues (ATOM records):

>d6zboe_ b.82.2.15 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
palklaleyivpcmnkhgicvvddflgketgqqigdevralhdtgdkitwiegkepgcet
igllmssmddlirhcngklgsykingrtkamvacypgngtgyvrhvdnpngdgrcvtciy
ylnkdwdakvsggilrifpegkaqfadiepkfdrllffwsdrrnphevqpayatryaitv
wyfdaderarakvkylt

Timeline for d6zboe_:

• d6zboe_ first appeared in SCOPe 2.07