Lineage for d6wu8b3 (6wu8 B:219-528)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2483040Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2483041Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2483697Family c.45.1.0: automated matches [191381] (1 protein)
    not a true family
  6. 2483698Protein automated matches [190475] (10 species)
    not a true protein
  7. 2483713Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)
  8. 2483858Domain d6wu8b3: 6wu8 B:219-528 [402738]
    Other proteins in same PDB: d6wu8a1, d6wu8a2, d6wu8b1, d6wu8b2
    automated match to d2b3oa3
    complexed with u9y

Details for d6wu8b3

PDB Entry: 6wu8 (more details), 2.4 Å

PDB Description: structure of human shp2 in complex with inhibitor iacs-13909
PDB Compounds: (B:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6wu8b3:

Sequence, based on SEQRES records: (download)

>d6wu8b3 c.45.1.0 (B:219-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsklaettdkvkqgfweefetlqqqeckllysrkegqrqenknknr
yknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnnskpkksyiatqgclqntv
ndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkesaahdytl
relklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvh
csagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymav
qhyietlqrr

Sequence, based on observed residues (ATOM records): (download)

>d6wu8b3 c.45.1.0 (B:219-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsqgfweefetlqqqeckllysrkegqrqenknknryknilpfdht
rvvlhdgsdyinaniimpefekksyiatqgclqntvndfwrmvfqensrvivmttkever
gkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrt
wpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiirek
gvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrr

SCOPe Domain Coordinates for d6wu8b3:

Click to download the PDB-style file with coordinates for d6wu8b3.
(The format of our PDB-style files is described here.)

Timeline for d6wu8b3: