SCOPe 2.08: Domain d7nr4a_: 7nr4 A:

Lineage for d7nr4a_ (7nr4 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.0: automated matches [191451] (1 protein)
   not a true family

6. Protein automated matches [190689] (87 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187871] (37 PDB entries)

8. Domain d7nr4a_: 7nr4 A: [402647]
   automated match to d4y30b_
   complexed with sah, uo2

Details for d7nr4a_

PDB Entry: 7nr4, 2.03 Å

PDB Description: x-ray structure of prmt6 in complex with indazole type inhibitor

PDB Compounds: (A:) Protein arginine N-methyltransferase 6

SCOPe Domain Sequences for d7nr4a_:

Sequence, based on SEQRES records:

>d7nr4a_ c.66.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tkrerdqlyyecysdvsvheemiadrvrtdayrlgilrnwaalrgktvldvgagtgilsi
fcaqagarrvyaveasaiwqqarevvrfngledrvhvlpgpvetvelpeqvdaivsewmg
ygllhesmlssvlhartkwlkegglllpasaelfivpisdqmlewrlgfwsqvkqhygvd
msclegfatrclmghseivvqglsgedvlarpqrfaqlelsragleqeleagvggrfrcs
cygsapmhgfaiwfqvtfpggesekplvlstspfhpathwkqallylnepvqveqdtdvs
geitllpsrdnprrlrvllrykvgdqeektkdfamed

Sequence, based on observed residues (ATOM records):

>d7nr4a_ c.66.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tkrerdqlyyecysdvsvheemiadrvrtdayrlgilrnwaalrgktvldvgagtgilsi
fcaqagarrvyaveasaiwqqarevvrfngledrvhvlpgpvetvelpeqvdaivsewmg
ygllhesmlssvlhartkwlkegglllpasaelfivpisdqmlewrlgfwsqvkqhygvd
msclegfatrclmghseivvqglsgedvlarpqrfaqlelsragleqeleagvggrfrcs
cygsapmhgfaiwfqvtfpgekplvlstspfhpathwkqallylnepvqveqdtdvsgei
tllpsrdnprrlrvllrykvgdqeektkdfamed

Timeline for d7nr4a_:

• d7nr4a_ first appeared in SCOPe 2.07