SCOPe 2.08: Domain d7nbmc_: 7nbm C:

Lineage for d7nbmc_ (7nbm C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.0: automated matches [191451] (1 protein)
   not a true family

6. Protein automated matches [190689] (87 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187871] (37 PDB entries)

8. Domain d7nbmc_: 7nbm C: [402520]
   Other proteins in same PDB: d7nbma2, d7nbmb2
   automated match to d3roda_
   complexed with u7k

Details for d7nbmc_

PDB Entry: 7nbm, 2.69 Å

PDB Description: co-crystal structure of human nicotinamide n-methyltransferase (nnmt) with the bisubstrate-like inhibitor (33)

PDB Compounds: (C:) Nicotinamide N-methyltransferase

SCOPe Domain Sequences for d7nbmc_:

Sequence, based on SEQRES records:

>d7nbmc_ c.66.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidig
sgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrvk
gpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrnl
gsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsys
stmanneglfslvarkl

Sequence, based on observed residues (ATOM records):

>d7nbmc_ c.66.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gftskdtylshfnprdylekyykfsaesqilkhllknlfkifcldgvkgdllidigsgpt
iyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrvkgpek
eeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrnlgsll
kpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsysstma
nneglfslvarkl

Timeline for d7nbmc_:

• d7nbmc_ first appeared in SCOPe 2.07