SCOPe 2.08: Domain d7ljub4: 7lju B:533-844

Lineage for d7ljub4 (7lju B:533-844)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein Dihydropyrimidine dehydrogenase, domain 4 [51410] (1 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [51411] (9 PDB entries)

8. Domain d7ljub4: 7lju B:533-844 [402260]
   Other proteins in same PDB: d7ljua1, d7ljua2, d7ljua3, d7ljua5, d7ljub1, d7ljub2, d7ljub3, d7ljub5, d7ljuc1, d7ljuc2, d7ljuc3, d7ljuc5, d7ljud1, d7ljud2, d7ljud3, d7ljud5
   automated match to d1gtea2
   complexed with fad, fnr, nap, sf4, y3g
   has additional subdomain(s) that are not in the common domain
   has additional insertions and/or extensions that are not grouped together

Details for d7ljub4

PDB Entry: 7lju, 1.87 Å

PDB Description: porcine dihydropyrimidine dehydrogenase (dpd) crosslinked with 5- ethynyluracil (5eu)

PDB Compounds: (B:) Dihydropyrimidine dehydrogenase [NADP(+)]

SCOPe Domain Sequences for d7ljub4:

Sequence, based on SEQRES records:

>d7ljub4 c.1.4.1 (B:533-844) Dihydropyrimidine dehydrogenase, domain 4 {Pig (Sus scrofa) [TaxId: 9823]}
isvemaglkfinpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivr
gttsgpmygpgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwme
lsrkaeasgadalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltp
nvtdivsiaraakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairp
ialravttiaralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyct
glkallylksie

Sequence, based on observed residues (ATOM records):

>d7ljub4 c.1.4.1 (B:533-844) Dihydropyrimidine dehydrogenase, domain 4 {Pig (Sus scrofa) [TaxId: 9823]}
isvemaglkfinpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivr
gttsgpmygpgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwme
lsrkaeasgadalelnlscacgqdpelvrnicrwvrqavqipffakltpnvtdivsiara
akeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravttiar
alpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylksi
e

Timeline for d7ljub4:

• d7ljub4 first appeared in SCOPe 2.07