Lineage for d7jx0a2 (7jx0 A:545-725)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2725421Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2725422Superfamily a.118.1: ARM repeat [48371] (28 families) (S)
  5. 2725640Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    automatically mapped to Pfam PF00613
    this is a repeat family; one repeat unit is 1e8y A:598-635 found in domain
  6. 2725641Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 2725642Species Human (Homo sapiens) [TaxId:9606] [48402] (77 PDB entries)
  8. 2725681Domain d7jx0a2: 7jx0 A:545-725 [402090]
    Other proteins in same PDB: d7jx0a1, d7jx0a3
    automated match to d1e8ya1
    complexed with vlv

Details for d7jx0a2

PDB Entry: 7jx0 (more details), 3.15 Å

PDB Description: nvs-pi3-4 bound to the pi3kg catalytic subunit p110 gamma
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d7jx0a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d7jx0a2 a.118.1.6 (A:545-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens) [TaxId: 9606]}
aempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeiv
aktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlv
qavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgc
g

SCOPe Domain Coordinates for d7jx0a2:

Click to download the PDB-style file with coordinates for d7jx0a2.
(The format of our PDB-style files is described here.)

Timeline for d7jx0a2: