SCOPe 2.05: Domain d1bzla3: 1bzl A:358-487

Lineage for d1bzla3 (1bzl A:358-487)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (11 proteins)

6. Protein Trypanothione reductase [55429] (3 species)

7. Species Trypanosoma cruzi [TaxId:5693] [55431] (4 PDB entries)

8. Domain d1bzla3: 1bzl A:358-487 [40192]
   Other proteins in same PDB: d1bzla1, d1bzla2, d1bzlb1, d1bzlb2
   complexed with fad, gcg

Details for d1bzla3

PDB Entry: 1bzl, 2.4 Å

PDB Description: crystal structure of trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors

PDB Compounds: (A:) trypanothione reductase (oxidized form)

SCOPe Domain Sequences for d1bzla3:

Sequence; same for both SEQRES and ATOM records:

>d1bzla3 d.87.1.1 (A:358-487) Trypanothione reductase {Trypanosoma cruzi [TaxId: 5693]}
dhtrvasavfsippigtcglieevaskryevvavylssftplmhkvsgskyktfvakiit
nhsdgtvlgvhllgdnapeiiqgigiclklnakisdfyntigvhptsaeelcsmrtpsyy
yvkgekmekp

Timeline for d1bzla3:

• d1bzla3 first appeared (with stable ids) in SCOP 1.55
  
• d1bzla3 appears in SCOPe 2.04
  
• d1bzla3 appears in SCOPe 2.06
  
• d1bzla3 appears in the current release, SCOPe 2.08