SCOPe 2.08: Domain d7avsa1: 7avs A:564-1042

Lineage for d7avsa1 (7avs A:564-1042)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (60 PDB entries)
   Uniprot Q07889 189-1046

8. Domain d7avsa1: 7avs A:564-1042 [401776]
   Other proteins in same PDB: d7avsa2
   automated match to d1nvus_
   complexed with imd, s3q

Details for d7avsa1

PDB Entry: 7avs, 2.28 Å

PDB Description: crystal structure of sos1 in complex with compound 6

PDB Compounds: (A:) Son of sevenless homolog 1

SCOPe Domain Sequences for d7avsa1:

Sequence, based on SEQRES records:

>d7avsa1 a.117.1.1 (A:564-1042) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnf
vrtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiq
pvqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkia
rdngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpse
lvgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfq
elnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsin
ppcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrv
esdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrp

Sequence, based on observed residues (ATOM records):

>d7avsa1 a.117.1.1 (A:564-1042) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifegipiikagtviklierltyhmyadpnfvrtfltt
yrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvl
nvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiardtfqss
pptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkein
spnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsa
mnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltni
lkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpm
gnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrp

Timeline for d7avsa1:

• d7avsa1 first appeared in SCOPe 2.07