SCOPe 2.08: Domain d7avia1: 7avi A:564-1044

Lineage for d7avia1 (7avi A:564-1044)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (60 PDB entries)
   Uniprot Q07889 189-1046

8. Domain d7avia1: 7avi A:564-1044 [401669]
   Other proteins in same PDB: d7avia2, d7avib2
   automated match to d1nvus_
   complexed with s2q

Details for d7avia1

PDB Entry: 7avi, 1.93 Å

PDB Description: crystal structure of sos1 in complex with compound 2

PDB Compounds: (A:) Son of sevenless homolog 1

SCOPe Domain Sequences for d7avia1:

Sequence, based on SEQRES records:

>d7avia1 a.117.1.1 (A:564-1044) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnf
vrtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiq
pvqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkia
rdngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpse
lvgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfq
elnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsin
ppcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrv
esdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrps
n

Sequence, based on observed residues (ATOM records):

>d7avia1 a.117.1.1 (A:564-1044) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifeenmgipiikagtviklierltyhmyadpnfvrtf
lttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvql
rvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiardnt
fqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtked
keinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvle
vvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiy
ltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffen
lnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsn

Timeline for d7avia1:

• d7avia1 first appeared in SCOPe 2.07